| Date & Time | Game | Venue |
|---|---|---|
| December 05, 2021 | (4) Essex Tech Hawks at (0) St. Paul Diocesan Knights
Garrett Reagan Summit |
New England Sports Center |
| December 11, 2021 | (1) St. Paul Diocesan Knights at (6) Assabet Aztecs | Navin Arena |
| December 14, 2021 | (6) Hopedale/Millis Blue Raiders at (1) St. Paul Diocesan Knights | Worcester Ice Center |
| December 18, 2021 | (6) Worcester/Leicester Wildcats at (3) St. Paul Diocesan Knights | Worcester Ice Center |
| December 22, 2021 | (7) Grafton Gators at (0) St. Paul Diocesan Knights | Worcester Ice Center |
| December 30, 2021 | (11) St. Paul Diocesan Knights at (1) St. Joseph Prep The Phoenix | Warrior Ice Arena |
| January 05, 2022 | (1) St. Paul Diocesan Knights at (2) Gardner/Murdock Wildcats | Gardner Veterans Skating Rink |
| January 12, 2022 | (1) St. Paul Diocesan Knights at (8) Hopedale/Millis Blue Raiders | Blackstone Valley Ice Arena |
| January 15, 2022 | (4) Northbridge Rams at (2) St. Paul Diocesan Knights | Worcester Ice Center |
| January 19, 2022 | (6) Assabet Aztecs at (2) St. Paul Diocesan Knights | Worcester Ice Center |
| January 22, 2022 | (3) Nashoba Tech at (2) St. Paul Diocesan Knights | Worcester Ice Center |
| January 24, 2022 | (2) St. Paul Diocesan Knights at (5) Northbridge Rams | New England Sports Center |
| January 31, 2022 | (3) St. Joseph Prep The Phoenix at (8) St. Paul Diocesan Knights | Worcester Ice Center |
| Feb. 4 Postponed | St. Paul Diocesan Knights at St. Bernard's Bernardians
Postponed: Make-Up TBA |
DCU Center |
| February 05, 2022 | (2) St. Paul Diocesan Knights at (9) Grafton Gators | Buffone Arena |
| February 09, 2022 | (1) St. Paul Diocesan Knights at (5) Worcester/Leicester Wildcats | Buffone Arena |
| February 16, 2022 | (2) St. Paul Diocesan Knights at (7) Worcester/Leicester Wildcats
Central MA Class B tournament |
Buffone Arena |
| February 23, 2022 | (4) St. Bernard's Bernardians at (5) St. Paul Diocesan Knights | Worcester Ice Center |
