| Date & Time | Game | Venue |
|---|---|---|
| December 11, 2021 | (4) Matignon Warriors at (6) Lowell Red Raiders
LOWELL HOLIDAY CLASSIC |
Tsongas Center |
| December 12, 2021 | (6) Danvers Falcons at (0) Lowell Red Raiders
LOWELL HOLIDAY CLASSIC |
Tsongas Center |
| December 14, 2021 | (4) Lowell Red Raiders at (10) Newton South Lions | John A. Ryan Arena |
| December 18, 2021 | (4) Boston Latin Wolfpack at (5) Lowell Red Raiders | Janas Memorial Rink |
| December 22, 2021 | (3) Lowell Red Raiders at (6) Concord-Carlisle Patriots | Edge Sports Center |
| January 08, 2022 | (0) Lowell Red Raiders at (8) Tewksbury Redmen | Breakaway Ice Center |
| January 12, 2022 | (6) Lincoln-Sudbury Warriors at (1) Lowell Red Raiders | Tsongas Center |
| January 15, 2022 | (5) Lowell Red Raiders at (4) Acton-Boxboro Revolution | Nashoba Valley Olympia |
| January 19, 2022 | (3) Newton South Lions at (1) Lowell Red Raiders | Tsongas Center |
| January 26, 2022 | (2) Concord-Carlisle Patriots at (1) Lowell Red Raiders | Tsongas Center |
| January 28, 2022 | (4) North Andover Scarlet Knights at (3) Lowell Red Raiders | Tsongas Center |
| February 01, 2022 | (1) Lowell Red Raiders at (3) Lowell Catholic Crusaders
Moved from 1/16/22 |
Tsongas Center |
| February 03, 2022 | (6) Tewksbury Redmen at (0) Lowell Red Raiders | Tsongas Center |
| February 05, 2022 | (1) Lowell Red Raiders at (4) Lincoln-Sudbury Warriors | New England Sports Center |
| February 10, 2022 | (4) Acton-Boxboro Revolution at (0) Lowell Red Raiders | Tsongas Center |
| February 12, 2022 | (2) Dracut/Tyngsboro Middies at (5) Lowell Red Raiders | Tsongas Center |
| February 13, 2022 | (3) Lowell Red Raiders at (6) North Andover Scarlet Knights | Haverhill Valley Forum |
| February 17, 2022 | (2) Lowell Red Raiders at (2) Boston Latin Wolfpack
re-scheduled from 1-22-22 |
Murphy Memorial Rink |
| February 20, 2022 | (0) Lowell Red Raiders at (1) Triton Vikings
NEWBURYPORT BANK ICE HOCKEY CLASSIC |
Graf Rink |
| February 22, 2022 | (8) Marblehead Magicians at (3) Lowell Red Raiders
NEWBURYPORT BANK ICE HOCKEY CLASSIC |
Graf Rink |
